2024 Genesis G80 Vs. Mercedes-Benz E 450: In-Depth Comparison
It's the battle of the luxury midsize sedans, and sitting pretty at the top of many drivers' shortlists are the Genesis G80 vs. Mercedes-Benz E 450. Both cars wrap you in a luxurious cocoon of high-end interior design, comfort, and convenience features in the cabin with a sleek outward design and performance-based mechanics, but only one model can emerge triumphant.
Take a stroll through the 2024 Genesis G80 vs. Mercedes-Benz E 450 trims, specs, interior features, dimensions, and safety ratings with our in-depth guide below to find your winner. If you crown the same champion we did – and we expect you might – we'll have your Genesis G80 test-drive keys waiting at Genesis of Atlanta!
Genesis G80 vs. Mercedes-Benz E 450 at a Glance
- The Genesis G80 configurations outpace the Mercedes-Benz E 450 in MSRP, max torque, safety scores, cabin space, and cargo capacity.
- The Genesis G80 has received IIHS Top Safety Pick+ awards every year since its debut,1 but the Mercedes-Benz E 450 missed a 2024 title and has spotty wins throughout its history.2
- The Genesis G80 offers two powertrain choices; you're limited to one powertrain in its Mercedes-Benz rival.
- Both models come in stunning exterior paint colors, but the Genesis G80 has captured our hearts with unique hues like Tasman Blue and Hallasan Green.
Genesis G80 vs. Mercedes-Benz E 450 Configurations
Athletic performance meets elegant design in both 2024 Genesis G80 models. Whether you prefer the 2.5T AWD configuration or the 3.5T AWD option, you can customize your Genesis G80 through three additional trim packages that are unique to your choice of powertrain. This plethora of options makes it clear that Genesis engineers are highly committed to helping drivers personalize their vehicles.
- Genesis G80 2.5T AWD: Available in Standard, Advanced, or Sport Prestige trims
- Genesis G80 3.5T AWD: Available in Sport, Sport Advanced, or Sport Prestige trims
Mercedes-Benz engineers redesigned the E Class for 2024, but even with these updates, the Mercedes-Benz E 450 still falls short of the luxurious Genesis G80. Only one powertrain fits both Mercedes-Benz trims, and although cabin features like 64-color LED ambient lighting are nice, they don't quite live up to the standard amenities you'll find in a new Genesis sedan. 2024 trims include:
- Mercedes-Benz E 450 Premium
- Mercedes-Benz E 450 Pinnacle
Genesis G80 vs. Mercedes-Benz E 450 Specs & Performance
With two powertrain options beneath its sleek hood, the 2024 Genesis G80 can hit a higher torque value than any Mercedes-Benz E 450 trim. In fact, with its 3.5-liter twin-turbo engine, the new Genesis sedan and its 391 pound-feet of torque outclasses other competitors, too, as evidenced in this Genesis G80 vs. Lexus ES 350 comparison.
All three Mercedes-Benz E 450 variants are powered by a 3.0-liter inline-six and a nine-speed transmission. Though the automaker likes to highlight the mild hybrid capabilities of this powertrain, we don't see much evidence of hybrid assistance in the Mercedes-Benz sedan's fuel economy. Compare Genesis G80 vs. Mercedes-Benz E 450 gas mileage, and you'll see that both deliver an EPA-estimated 22 MPG on city streets.3, 4
2024 Genesis G80 |
2024 Mercedes-Benz E 450 |
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| New Vehicle Limited Warranty | 5-yr / 60,000-mi5 | 4-yr / 50,000-mi5 |
| NHTSA Rating | 5-star6 | Not rated |
| IIHS Safety Award | IIHS Top Safety Pick+1 | N / A |
| Engine | 2.5L turbo inline 4-cyl 3.5L twin-turbocharged V-6 |
3.0L inline-6 turbo w/ mild hybrid drive |
| Horsepower | 300 (2.5L) 375 (3.5L) |
375 |
| Torque | 311 lb-ft (2.5L) 391 lb-ft (3.5L) |
369 lb-ft |
| Transmission | 8-speed automatic | 9-speed automatic |
| Drivetrain | AWD | 4MATIC® AWD |
| EPA-Est. MPG (Cty / Hwy / Comb) | 22 / 30 / 253 (2.5L) 16 / 25 / 193 (3.5L) |
22 / 31 / 354 |
| 0-60 mph Acceleration Time | 5.7 sec7 (2.5L) 4.9 sec7 (3.5L) |
4.4 sec |
| Fuel Tank Capacity | 17.2 gal | 17.4 gal |
| Exterior Length | 196.7 in | 194.9 in |
| Passenger Seating | 5 | 5 |
| Maximum Front Headroom / Legroom | 41.1 / 42.2 in | 37.3 / 41.5 in |
| Curb Weight | 4,112 lbs | 4,376 lbs |
| Cargo Capacity | 13.1 cu ft | 12.7 cu ft |
| Standard Interior Features |
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| Standard Exterior Features |
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| Standard Safety Features |
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Genesis G80 vs. Mercedes-Benz E 450 Interior
As you might expect, the Genesis G80 vs. Mercedes-Benz E 450 sedans showcase heated front seats, but only the Genesis model gives you heated rear seats as standard in its base model. The Genesis G80 2.5T AWD is a masterclass in entry-level design, giving drivers the elevated features they crave. Take a look at some of the incredible features you'll find in the new Genesis G80 for sale:
- Supple leatherette or leather upholstery
- 14.5-inch HD touch screen
- Integrated navigation system
- Gorgeous full-cabin panoramic sunroof
- Wireless phone charging
- Surround View Monitor
In comparison, the standard Mercedes-Benz E 450 Premium trim features a smaller 14.4-inch touch screen and a decidedly less exciting cabin design. The base model Mercedes-Benz E 450 Premium edition comes with the following standard features, but you'll need to bump up your budget considerably to access the Head-Up Display, noise-insulated glass, and active ambient lighting of the top-tier Mercedes-Benz E 450 Pinnacle.
- "Hey, Mercedes" keyword activation
- Wireless phone charging
- Panorama roof
- Driver camera
- MB Navigation
Genesis G80 vs. Mercedes-Benz E 450 Dimensions & Cargo Space
One look at the Mercedes-Benz E 450 vs. Genesis G80 dimensions and it's clear that the Genesis sedan will make daily life much easier. Although both the Genesis G80 and Mercedes-Benz E 450 offer seating for five, the Genesis trims put their additional 1.8 feet of exterior length to good use by offering additional cargo space you just won't find in its competition.
The Mercedes-Benz cabin is also considerably smaller: Front-seat passengers need to squeeze into only 37.3 inches of headroom and 41.5 inches of legroom. In stark contrast, front occupants in any Genesis G80 trim with a panoramic sunroof can relax with up to 41.1 inches of headroom and stretch out on long road trips with 42.2 inches of leg space. Even without the sunroof, you'll get 39.4 inches of front headroom, beating out the Mercedes-Benz E 450 by 2.1 inches.
Genesis G80 vs. Mercedes-Benz E 450 Reliability & Safety
Unfortunately, the Mercedes-Benz E 450 falls short yet again by luxury reliability and safety standards. The 2024 Genesis G80 provides standard features on both its powertrains and in all three trims that keep you confident on the road, including Lane Keeping Assist, Lane Follow Assist, and Rear Cross-Traffic Collision-Avoidance Assist – none of which come standard in the entry-level Mercedes-Benz E 450.
If you want a truly safety-inspired vehicle, you want the following standard features of the new Genesis G80, along with the three mentioned above:
- Highway Driving Assist 2
- Safe Exit Assist
- High Beam Assist
- Smart Cruise Control
- Forward Collision-Avoidance Assist
- Driver Attention Warning
- Blind-Spot Collision-Avoidance Assist
- Parking Distance Warning
- Rearview Camera
In addition, the 2024 Genesis G80 has captured IIHS Top Safety Pick+ awards every single year since its debut, including 2024,1 whereas the 2024 Mercedes-Benz E 450 has not ranked for an IIHS award.2
Unlock Luxury Power in a New Genesis G80
We know both models in the 2024 Mercedes-Benz E 450 vs. Genesis G80 comparison have so much to offer, and your final decision won't be easy. We do hope our comparison guide has been helpful, and we're confident in the Genesis G80 and its ability to outperform its Mercedes-Benz rival in key categories like cargo capacity, cabin space, safety scores, and starting MSRPs.
You'll save big on this stunning new Genesis sedan with our Genesis G80 lease deals, so visit Genesis of Atlanta for a test drive!
Frequently Asked Questions
Which is more luxurious: the Genesis G80 or the Mercedes-Benz E 450?
Thanks to its elevated safety features, larger center touch screen, and enhanced standard technology like Smart Cruise Control, the 2024 Genesis G80 takes the title of most luxurious sedan. Even Genesis G80 vs. Mercedes-Benz E 450 dimensions make it obvious that the larger Genesis cabin is where you'll want to be. Find the more elegant Genesis G80 at Genesis of Atlanta!
Which has more interior room: the Mercedes-Benz E 450 or the Genesis G80?
The 2024 Genesis G80 has more front headroom and legroom than the new Mercedes-Benz E 450, making it the comfortable choice for weekday commutes or weekend getaways. You'll also notice that the Genesis G80 trunk is larger, so packing for trips – or even just hauling groceries and gear – should be easier in your Genesis sedan than in either of the Mercedes-Benz E 450 trims.
Which has better fuel economy: the Genesis G80 or the Mercedes-Benz E 450?
The Genesis G80 vs. Mercedes-Benz E 450 have identical city fuel economy, offering an EPA-estimated 22 MPG when commuting on city streets.3, 4 Highway gas mileage is evenly matched as well, with the 2024 Mercedes-Benz sedan offering an EPA-estimated 31 MPG4 and the Genesis model capable of an EPA-estimated 30 MPG.3 Experience the Genesis G80 capabilities in person with a spirited test drive!
1Reference to this third-party claim is solely for informational purposes and not to be relied upon. For details regarding this award, visit https://www.iihs.org/ratings/vehicle/Genesis/g80-4-door-sedan/2024
2Reference to this third-party claim is solely for informational purposes and not to be relied upon. For details regarding this award, visit https://www.iihs.org/ratings/vehicle/mercedes-benz/e-class-4-door-sedan/2023
3All figures are EPA estimates and for comparison purposes only. Actual mileage may vary with options, driving conditions, driving habits and vehicle's condition.
4EPA-estimated fuel economy. Compare the estimated MPG to the estimated MPG of other vehicles. You may get different mileage depending on how fast you drive, weather conditions and trip length. Your actual highway mileage will probably be less than the highway estimate.
5Warranties listed on this web page shall not be solely relied upon. Warranties may be subject to specific terms, restrictions, exclusions, and fees. Additional warranty information may be obtained by visiting the official website of the warranty provider. Contact our dealership for complete details.
6Reference to this third-party claim is solely for informational purposes and not to be relied upon. For details regarding this rating, visit https://www.nhtsa.gov/press-releases/nhtsa-2024-crash-test-vehicles-5-star-safety-ratings
7This information is not verified by the official manufacturer and shall serve solely as unofficial general information. For details, visit: https://www.caranddriver.com/genesis/g80-2024